Accumulating Oocytes or Blastocysts for Low Responders? Age as a Criterion.
Several studies have shown maternal age as a determining factor in IVF treatment.
Most of our patient are suffered from diminished ovarian reserve and/or advanced maternal age. For women over 38-year-old, with declined ovarian reserve, accumulating blastocysts is the strategy we use. Both the quality and quantity of oocytes are adversely affected by the age. They may experience repeated IVF failure caused by few or no embryos to transfer. In this cohort, accumulating blastocysts could be used to increase the chance of pregnancy.
What is oocytes accumulation? What is blastocysts accumulation?
Oocytes accumulation aimed at collecting oocytes, and freeze it. After we had collected enough oocytes, we thaw all oocytes and fertilize and culture them in one batch.
Blastocysts accumulation aimed at creating blastocysts and freeze it. After each oocyte retrieval surgery, we fertilize the eggs and culture till day 5~6 then freeze it.
The clinical outcomes of different age using different treatment shown.
The result indicated that in using oocytes accumulation, the pregnancy rate of the patient over 38 y/o is 2-3 times less than the patient below 38 y/o.
But the pregnancy rate of oocytes or blastocyst accumulation did not show a significant difference.
To conclude, for age under 38y/o, the pregnancy rate can be reached around 50~70% regardless of what treatment is used; however, forage over 38y/o, the pregnancy rate will be double using blastocyst instead of oocyte
the pregnancy rate of age over 38y/o is nearly double that of the ovulation pregnancy rate.
How many blastocysts should I collect?
Without pre-implantation genetic screening(PGS), the basis for embryo implantation can only be judged by the developmental speed and appearance level.
Therefore, the pregnancy rate and live birth rate vary with age.
The estimated fee for both treatments is as follow.
To increase the pregnancy rate and live birth rate furthermore, we introduce you the Third generation IVF Plus( PGS + ERA) . For further require, please contact us
Leave a message down below, we are more than willing to answer!